Article
A European pharmacogenomic study of the response to opioids in advanced cancer patients identifies germline variants associated with nausea-vomiting side effect
2024-03-29
Abstract excerpt
<title>Abstract</title> <p>Opioids are the mainstay therapy for patients affected by moderate to severe cancer pain, yet in about 10–20% of the cases, patients do not benefit from the received analgesic treatment or experience side effects. Genetic variability might account for the variation in individual responses to opioids, both in terms of efficacy and toxicity. The aim of this genome-wide association study (...
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Identifiers and source
- Literature Corpus work
- 008c4ef3-7b3d-5795-ad17-ce9b09b4da96
- DOI
- 10.21203/rs.3.rs-4174606/v1