Article
TMEM132C rs7296262 Single-Nucleotide Polymorphism Is Significantly Associated with Nausea Induced by Opioids Administered for Cancer Pain and Postoperative Pain.
International journal of molecular sciences - 14 Aug 2024
Kang Yuna, Nishizawa Daisuke, Ohka Seii, Terui Takeshi, Ishitani Kunihiko, Morino Ryozo, Yokota Miyuki, Hasegawa Junko, Nakayama Kyoko, Ebata Yuko, Koshika Kyotaro, Ichinohe Tatsuya, Ikeda Kazutaka
Abstract excerpt
Opioids are almost mandatorily used for analgesia for cancer pain and postoperative pain. Opioid analgesics commonly induce nausea as a side effect. However, the genetic factors involved are still mostly unknown. To clarify the genetic background of individual differences in the occurrence of nausea during opioid administration, the incidence of nausea was investigated in 331 patients (Higashi-Sapporo Hospital...
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