TrimNN: Characterizing cellular community motifs for studying multicellular topological organization in complex tissues

Abstract excerpt

<title>Abstract</title> <p>The spatial arrangement of cells plays a pivotal role in shaping tissue functions in various biological systems and diseased microenvironments. However, it is still under-investigated of the topological coordinating rules among different cell types as tissue spatial patterns. Here, we introduce the Triangulation cellular community motif Neural Network (TrimNN), a bottom-up approach to e...

Topics

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• Algorithms
• Cluster Analysis
• Ecology
• Histological Techniques
• Machine Learning
• Neural Networks, Computer
• Phenotype

Identifiers and source

Literature Corpus work

00742b68-7f4c-508a-bfda-a8d2725de5b1

DOI

10.21203/rs.3.rs-5584635/v1