Article

Learning predictive models of tissue cellular neighborhoods from cell phenotypes with graph pooling

2022-11-06

Abstract excerpt

It remains poorly understood how different cell types organize and coordinate with each other to support tissue functions. We describe CytoCommunity for identification of tissue cellular neighborhoods (TCNs) based on cell phenotypes and their spatial distributions. CytoCommunity learns a mapping directly from cell phenotype space to TCN space by a graph neural network model without using additional gene or protein...

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Literature Corpus work: 4a0c872e-4bf5-5ecd-bf0a-eb6c9f611cad
DOI: 10.1101/2022.11.06.515344

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