TrimNN: Characterizing cellular community motifs for studying multicellular topological organization in complex tissues

Abstract excerpt

<h4>ABSTRACT</h4> The spatial organization of cells plays a pivotal role in shaping tissue functions and phenotypes in various biological systems and diseased microenvironments. However, the topological principles governing interactions among cell types within spatial patterns remain poorly understood. Here, we present the Tri angulation Cellular Community M otif N eural N etwork ( TrimNN ), a graph-based de...

Topics

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• Algorithms
• Cluster Analysis
• Neural Networks, Computer
• Phenotype

Identifiers and source

Literature Corpus work

23fc23f9-e970-5fd3-8007-879d78aaac63

DOI

10.1101/2024.12.19.629384