Article

Longitudinal profiling of circulating tumour DNA for tracking tumour dynamics in pancreatic cancer

2021-01-15

Abstract excerpt

The utility of circulating tumour DNA (ctDNA) for longitudinal tumour monitoring in pancreatic ductal adenocarcinoma (PDAC) has not been explored beyond mutations in the KRAS proto-oncogene. Here, we follow 3 patients with resectable disease and 4 patients with advanced unresectable disease, using exome sequencing of resected tissues and plasma samples (n=20) collected over a ∼2-year period from diagnosis through...

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Literature Corpus work: 0068f71f-72d6-5db6-bfb9-e2ba05804baf
DOI: 10.1101/2021.01.13.20248620

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