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Article

Comprehensive ctDNA Measurements Improve Prediction of Clinical Outcomes and Enable Dynamic Tracking of Disease Progression in Advanced Pancreatic Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 3 Apr 2023

Lapin Morten, Edland Karin H, Tjensvoll Kjersti, Oltedal Satu, Austdal Marie, Garresori Herish, Rozenholc Yves, Gilje Bjørnar, Nordgård Oddmund

Abstract excerpt

PURPOSE: Circulating tumor DNA (ctDNA) has emerged as a promising tumor-specific biomarker in pancreatic cancer, but current evidence of the clinical potential of ctDNA is limited. In this study, we used comprehensive detection methodology to explore the utility of longitudinal ctDNA measurements in patients with advanced pancreatic cancer. EXPERIMENTAL DESIGN: A targeted eight-gene next-generation sequencing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36662807
DOI: 10.1158/1078-0432.CCR-22-3526
PMCID: PMC10068442

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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