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Article

Longitudinal profiling of circulating tumour DNA for tracking tumour dynamics in pancreatic cancer.

BMC cancer - 7 Apr 2022

Sivapalan Lavanya, Thorn Graeme J, Gadaleta Emanuela, Kocher Hemant M, Ross-Adams Helen, Chelala Claude

Abstract excerpt

BACKGROUND: The utility of circulating tumour DNA (ctDNA) for longitudinal tumour monitoring in pancreatic ductal adenocarcinoma (PDAC) has not been explored beyond mutations in the KRAS proto-oncogene. Here, we aimed to characterise and track patient-specific somatic ctDNA variants, to assess longitudinal changes in disease burden and explore the landscape of actionable alterations. METHODS: We followed 3...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35392854
DOI: 10.1186/s12885-022-09387-6
PMCID: PMC8991893

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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