Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The conformation of tetraspanins CD53 and CD81 differentially affects their nanoscale organization and interaction with their partners.

The Journal of biological chemistry - 1 Sept 2024

Schwerdtfeger Fabian, Hoogvliet Ilse, van Deventer Sjoerd, van Spriel Annemiek B

Abstract excerpt

Tetraspanins, including CD53 and CD81, are four-transmembrane proteins that affect the membrane organization to regulate cellular processes including migration, proliferation, and signaling. However, it is unclear how the organizing function of tetraspanins is regulated at the molecular level. Here, we investigated whether recently proposed "open" and "closed" conformations of tetraspanins regulate the nanoscale...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Membrane
Share to Leukocyte Common Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Protein Binding

Share to Protein Conformation

Share to Tetraspanin 28

Source

Open in PubMed Open full text

Identifiers

PMID: 39159818
DOI: 10.1016/j.jbc.2024.107685
PMCID: PMC11416636

Genes

CD81
CD53
CD19

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The conformation of tetraspanins CD53 and CD81 differentially affects their nanoscale organization and interaction with their partners.PMID 39159818Read ↗

The tetraspanin web revisited by super-resolution microscopySemantic proximity Read ↗

Microscopic clusters feature the composition of biochemical tetraspanin-assemblies and constitute building-blocks of tetraspanin enriched domainsSemantic proximity Read ↗

Tetraspanins at a glanceSemantic proximity Read ↗

Cryo-EM structure of the B cell co-receptor CD19 bound to the tetraspanin CD81.Semantic proximity Read ↗

Single-molecule localization microscopy reveals the molecular organization of endogenous membrane receptorsSemantic proximity Read ↗

Proteomic landscape of tunneling nanotubes reveals CD9 and CD81 tetraspanins as key regulatorsSemantic proximity Read ↗

Proteomic landscape of tunneling nanotubes reveals CD9 and CD81 tetraspanins as key regulatorsSemantic proximity Read ↗

Tetraspanin Proteins Mediate Cellular Penetration, Invasion, and Fusion Events and Define a Novel Type of Membrane MicrodomainSemantic proximity Read ↗

Site-specific functionality and tryptophan mimicry of lipidation in tetraspanin CD9.Semantic proximity Read ↗

Antigen Receptor Nanoclusters: Small Units with Big Functions.Semantic proximity Read ↗

Glycosylation differentially affects immune cell-specific tetraspanins CD37 and CD53Semantic proximity Read ↗

Tetraspanins affect membrane structures and the trafficking of molecular partners: what impact on extracellular vesicles?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.