Article

An iterative supervised learning method identifying two subgroups of FOLFOX resistance patterns and predicting FOLFOX response in colorectal cancer patients

2020-06-11

Abstract excerpt

<h4>Background</h4> FOLFOX is a combination of drugs that is widely used to treat colorectal cancer. The response rate of FOLFOX in colorectal cancer(CRC) is 30-50%. We develop a method that analyzes mechanisms of FOLFOX resistance and predicts whether a patient will benefit from FOLFOX. <h4>Methods</h4> Gene expression data of 83 stage IV CRC tumor samples (FOLFOX responder n=42, non-responder n=41) were used to...

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Literature Corpus work: 0024978f-6e30-5d8f-86b8-0d1cf869da16
DOI: 10.1101/2020.06.10.20127167

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