Article
A tumor microenvironment-specific gene expression signature predicts chemotherapy resistance in colorectal cancer patients
12 Feb 2021
Abstract excerpt
Studies have shown that tumor microenvironment (TME) might affect drug sensitivity and the classification of colorectal cancer (CRC). Using TME-specific gene signature to identify CRC subtypes with distinctive clinical relevance has not yet been tested. A total of 18 "bulk" RNA-seq datasets (total n = 2269) and four single-cell RNA-seq datasets were included in this study. We constructed a "Signature associated...
Topics
Join the communities discussing this publication.