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Identification of a six-gene signature predicting overall survival for Oxaliplatin and 5-Fluorouracil resistant Colon cancer and potential drug-repurposing

2020-07-21

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<title>Abstract</title> <p>Background Oxaliplatin (L-OHP) and 5-fluorouracil (5-FU) resistance in colorectal cancer (CRC) is a major medical problem. Therefore, detailed mechanisms and predictive markers are urgently needed. The aim of this study was to identify key pathways, a robust prognostic gene signature and potential drug-repurposing. Methods In order to confirm the predictive markers and detailed molecu...

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Literature Corpus work
edfcf4a4-9727-5b08-96c5-c1cfa6275dd4
DOI
10.21203/rs.3.rs-43698/v1
Open publication

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Identification of a six-gene signature predicting overall survival for Oxaliplatin and 5-Fluorouracil resistant Colon cancer and potential drug-repurposingDOI 10.21203/rs.3.rs-43698/v1
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