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Identification of a Six-Gene Signature Predicting Overall Survival for Oxaliplatin and 5-Fluorouracil Resistant Colon Cancer and Potential Drug-Repurposing

2020-07-16

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<title>Abstract</title> <p><bold>Background: </bold>Oxaliplatin (L-OHP) and 5-fluorouracil (5-FU) resistance in colorectal cancer (CRC) is a major medical problem. Therefore, detailed mechanisms and predictive markers are urgently needed. The aim of this study was to identify key pathways, a robust prognostic gene signature and potential drug-repurposing. <bold>Methods: </bold>In order to confirm the predictive m...

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Literature Corpus work
4e287a94-814a-5755-b09a-33f44421c961
DOI
10.21203/rs.3.rs-41005/v1
Open publication

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Identification of a Six-Gene Signature Predicting Overall Survival for Oxaliplatin and 5-Fluorouracil Resistant Colon Cancer and Potential Drug-RepurposingDOI 10.21203/rs.3.rs-41005/v1
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