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Integrated Bioinformatics Analysis of the Hub Genes Involved in Irinotecan Resistance in Colorectal Cancer

16 Jul 2022

Abstract excerpt

Different drug combinations including irinotecan remain some of the most important therapeutic modalities in treating colorectal cancer (CRC). However, chemotherapy often leads to the acquisition of cancer drug resistance. To bridge the gap between in vitro and in vivo models, we compared the mRNA expression profiles of CRC cell lines (HT29, HTC116, and LoVo and their respective irinotecan-resistant variants)...

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Share to Colorectal Cancer Treatments and Studies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35885025
DOI: 10.3390/biomedicines10071720

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