Article
Irinotecan Resistance – In Search of New Markers in CRC.
2021-12-10
Abstract excerpt
Colorectal cancer (CRC) is one of the most prominent causes of cancer death worldwide. Chemotherapeutic regimens consisting of different drugs combinations such as 5-fluorouracil, and oxaliplatin (FOLFOX) or irinotecan (FOLFIRI) have been proven successful in the treatment of CRC. However, chemotherapy often leads to the acquisition of cancer drug resistance followed by metastasis and in the aftermath therapeutic...
Topics
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- Cancer therapeutics and mechanisms
- Colorectal Cancer Treatments and Studies
- Computational Drug Discovery Methods
- Drug Transport and Resistance Mechanisms
- Genetic factors in colorectal cancer
- Genomics, phytochemicals, and oxidative stress
- Hepatocellular Carcinoma Treatment and Prognosis
- MicroRNA in disease regulation
Identifiers and source
- Literature Corpus work
- 61bafec6-52b5-5217-ba49-d3c52e836dc8
- DOI
- 10.21203/rs.3.rs-1088696/v1
