Article

YPEL controls synapse development through p62-Nrf2 antioxidant pathway in <i>Drosophila</i> neuromuscular junction

2025-04-07

Abstract excerpt

The Yippee-like ( YPEL ) genes are highly conserved among all eukaryotic species, yet the molecular and cellular pathways that YPEL regulate are poorly understood. Human and animal studies suggest that YPEL is involved in nervous system functions. Here we report that YPEL is necessary for synapse development in neuromuscular junction and motor functions in Drosophila . YPEL interacts with the Drosophila p62, R...

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Literature Corpus work: 0012b2eb-aaf2-5a68-a3fc-63c4b66e4b85
DOI: 10.1101/2025.04.07.647271

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YPEL controls synapse development through p62-Nrf2 antioxidant pathway in <i>Drosophila</i> neuromuscular junctionDOI 10.1101/2025.04.07.647271Read

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