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Article

Identifying potential PARIS homologs in D. melanogaster.

Genetics and molecular research : GMR - 3 Nov 2016

Merzetti E M, Staveley B E

Abstract excerpt

Mitochondrial destruction leads to the formation of reactive oxygen species, increases cellular stress, causes apoptotic cell death, and involves a cascade of proteins including PARKIN, PINK1, and Mitofusin2. Mitochondrial biogenesis pathways depend upon the activity of the protein PGC-1α. These two processes are coordinated by the activity of a transcriptional repressor, Parkin interacting substrate (PARIS). The...

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Source

Identifiers

PMID: 27819722
DOI: 10.4238/gmr15048934

Genes

PGC
PINK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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