Article
Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria.
Journal of acquired immune deficiency syndromes (1999) - 1 Oct 2009
Hawkins Claudia A, Chaplin Beth, Idoko John, Ekong Ernest, Adewole Isaac, Gashau Wadzani, Murphy Robert L, Kanki Phyllis
Abstract excerpt
INTRODUCTION: The HIV-1 epidemic in African countries is largely due to non-B HIV-1 subtypes. Patterns and frequency of antiretroviral drug resistance mutations observed in these countries may differ from those in the developed world, where HIV-1 subtype B predominates. METHODS: HIV-1 subtype and drug resistance mutations were assayed among Nigerian patients with treatment failure on first-line therapy (plasma...
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