Article
Natural polymorphisms in HIV-1 CRF01_AE strain and profile of acquired drug resistance mutations in a long-term combination treatment cohort in northeastern China.
BMC infectious diseases - 26 Feb 2020
Sun Zesong, Ouyang Jinming, Zhao Bin, An Minghui, Wang Lin, Ding Haibo, Han Xiaoxu
Abstract excerpt
BACKGROUND: The impacts of genetic polymorphisms on drug resistance mutations (DRMs) among various HIV-1 subtypes have long been debated. In this study, we aimed to analyze the natural polymorphisms and acquired DRM profile in HIV-1 CRF01_AE-infected patients in a large first-line antiretroviral therapy (ART) cohort in northeastern China. METHODS: The natural polymorphisms of CRF01_AE were analyzed in 2034...
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