Article
K65R with and without S68: a new resistance profile in vivo detected in most patients failing abacavir, didanosine and stavudine.
Antiviral therapy - 1 Apr 2003
Røge Birgit T, Katzenstein Terese L, Obel Niels, Nielsen Henrik, Kirk Ole, Pedersen Court, Mathiesen Lars, Lundgren Jens, Gerstoft Jan
Abstract excerpt
Antiretroviral treatment with three nucleoside reverse transcriptase inhibitors (NRTIs) is widely used, but the combination of abacavir, didanosine and stavudine has never been investigated. We describe the surprising and consistent genotypic and phenotypic outcome in patients failing this combination. As part of a Danish multicentre study, 60 antiretroviral-naive patients were randomized to treatment with...
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