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HMGCS2 is a key ketogenic enzyme potentially involved in type 1 diabetes with high cardiovascular risk

28 Jun 2017

Abstract excerpt

Diabetes increases the risk of Cardio-vascular disease (CVD). CVD is more prevalent in type 2 diabetes (T2D) than type 1 diabetes (T1D), but the mortality risk is higher in T1D than in T2D. The pathophysiology of CVD in T1D is poorly defined. To learn more about biological pathways that are potentially involved in T1D with cardiac dysfunction, we sought to identify differentially expressed genes in the T1D heart....

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PMID: 28676675
DOI: 10.1038/s41598-017-04469-z

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