Article

Single nucleus RNA-sequencing study revealed expansion of Gpnmb+ microglia in aged mouse spinal cord

2023-10-03

Abstract excerpt

<title>Abstract</title> <p>Neurodegenerative diseases tend to occur later in life, and studies of central nervous system (CNS) aging could deepen our understanding of those diseases. In this study, we profiled the transcriptomes of 71,144 spinal cord cells from both of young and old mice, and identified 1, 215 aging-associated differentially expressed genes, including up regulation of C4b and Gfap. Interestingly,...

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Literature Corpus work: 000b358d-02b4-5bf2-9db6-6d81075f46cb
DOI: 10.21203/rs.3.rs-3333031/v1

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