Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular characterization of a locus required for hyaluronic acid capsule production in group A streptococci.

1 May 1992

Abstract excerpt

To characterize the production of hyaluronate capsule by the membrane-associated enzyme hyaluronate synthase (HAS), group A streptococci from a recent outbreak of acute rheumatic fever were mutagenized via Tn916 insertion. Acapsular transconjugants harboring multiple, nontandem copies of the transposon were identified and found to lack HAS activity (less than 1% of wild-type levels). Generalized transduction was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Herpesvirus Infections and Treatments
Share to Microbial infections and disease research
Share to Streptococcal Infections and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1569398
DOI: 10.1084/jem.175.5.1291

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular characterization of a locus required for hyaluronic acid capsule production in group A streptococci.PMID 1569398Read ↗

Effects on virulence of mutations in a locus essential for hyaluronic acid capsule expression in group A streptococci.Semantic proximity Read ↗

Isolation of a Streptococcus pyogenes gene locus that directs hyaluronan biosynthesis in acapsular mutants and in heterologous bacteria.Semantic proximity Read ↗

Hyaluronic acid capsule is a virulence factor for mucoid group A streptococci.Semantic proximity Read ↗

Asymptomatic carriage of group A streptococcus is associated with elimination of capsule production.Semantic proximity Read ↗

Hyaluronic Acid Synthesis Operon (has) Expression in Group A StreptococciSemantic proximity Read ↗

Critical role of the group A streptococcal capsule in pharyngeal colonization and infection in mice.Semantic proximity Read ↗

Identification of <i>csrR/csrS</i>, a genetic locus that regulates hyaluronic acid capsule synthesis in group A <i>Streptococcus</i>Semantic proximity Read ↗

Characterization of a two-component system in Streptococcus pyogenes which is involved in regulation of hyaluronic acid production.Semantic proximity Read ↗

Expression and contribution to virulence of each polysaccharide capsule of Bacillus cereus strain G9241.Semantic proximity Read ↗

Hyaluronan release from Streptococcus pyogenes: export by an ABC transporter.Semantic proximity Read ↗

Molecular characterization of hasC from an operon required for hyaluronic acid synthesis in group A streptococci. Demonstration of UDP-glucose pyrophosphorylase activity.Semantic proximity Read ↗

Identification and disruption of two discrete loci encoding hyaluronic acid capsule biosynthesis genes hasA, hasB, and hasC in Streptococcus uberis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.