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Article

Hyaluronic Acid Synthesis Operon (has) Expression in Group A Streptococci

1 Aug 1995

Abstract excerpt

The has operon is composed of three genes, hasA, hasB, and hasC that encode hyaluronate synthase, UDP-glucose dehydrogenase, and presumptively UDP-glucose pyrophosphorylase, respectively. Expression of the has operon was shown to be required for the synthesis of the hyaluronic acid capsule in group A streptococci. Previous studies indicated that some group A and group C streptococcal strains produce the...

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PMID: 7629171
DOI: 10.1074/jbc.270.31.18452

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Hyaluronic Acid Synthesis Operon (has) Expression in Group A StreptococciPMID 7629171Read ↗

Molecular characterization of hasC from an operon required for hyaluronic acid synthesis in group A streptococci. Demonstration of UDP-glucose pyrophosphorylase activity.Semantic proximity Read ↗

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Mutual Exclusivity of Hyaluronan and Hyaluronidase in Invasive Group A StreptococcusSemantic proximity Read ↗

Characterization of a two-component system in Streptococcus pyogenes which is involved in regulation of hyaluronic acid production.Semantic proximity Read ↗

Structure of the <i>has</i> operon promoter and regulation of hyaluronic acid capsule expression in group A <i>Streptococcus</i>Semantic proximity Read ↗

Isolation of a Streptococcus pyogenes gene locus that directs hyaluronan biosynthesis in acapsular mutants and in heterologous bacteria.Semantic proximity Read ↗

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