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Article

Thrombospondin-1, PECAM-1, and regulation of angiogenesis.

Histology and histopathology - 1 Jan 1999

Sheibani N, Frazier W A

Abstract excerpt

Thrombospondin-1 (TSP1) is a multidomain glycoprotein expressed by many cell types. It is a multifunctional protein with important roles in regulation of vascular cell functions. Mutation or loss of tumor suppressor genes results in down regulation of TSP1 expression during malignant transformation. Thus, suggesting that down regulation of TSP1 may contribute to development of the tumor angiogenic phenotype and...

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Identifiers

PMID: 9987673
DOI: 10.14670/HH-14.285

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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