Article
Thrombospondin-1 is a plasmatic marker of peripheral arterial disease that modulates endothelial progenitor cell angiogenic properties.
Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2011
Smadja David M, d'Audigier Clément, Bièche Ivan, Evrard Solène, Mauge Laetitia, Dias Juliana-Vieira, Labreuche Julien, Laurendeau Ingrid, Marsac Bérengère, Dizier Blandine, Wagner-Ballon Orianne, Boisson-Vidal Catherine, Morandi Verônica, Duong-Van-Huyen Jean-Paul, Bruneval Patrick, Dignat-George Françoise, Emmerich Joseph, Gaussem Pascale
Abstract excerpt
OBJECTIVE: We examined whether plasma levels of angiogenic factors are altered in plasma of patients with peripheral arterial disease (PAD) and whether these factors affect endothelial progenitor cell-induced angiogenesis. METHODS AND RESULTS: Plasma was collected from 184 patients with PAD and 330 age-matched healthy controls. Vascular endothelial growth factor and placental growth factor concentrations did not...
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