Context-dependent immunogenicity of an S206G-substituted H-2Db-restricted simian virus 40 large T antigen epitope I variant.

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Article

Context-dependent immunogenicity of an S206G-substituted H-2Db-restricted simian virus 40 large T antigen epitope I variant.

Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 1999

Mylin L M

Abstract excerpt

SV40 large tumor Ag (Tag) contains four H-2b-restricted (I, II/III, IV, and V) CTL epitopes. A hierarchy exists among these CTL epitopes. CTL directed against epitopes I, II/III, and IV are readily detected following immunization of H-2b mice with SV40, Tag-transformed syngeneic cells, or a vacci...

Topics

Amino Acid Sequence
Amino Acid Substitution
Animals
Antigen Presentation
Antigens, Viral, Tumor
Clone Cells
Epitopes, T-Lymphocyte
Genetic Variation
Glycine
H-2 Antigens
Histocompatibility Antigen H-2D
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Molecular Sequence Data

Mutagenesis, Site-Directed

Serine

Simian virus 40

T-Lymphocytes

Source

Open in PubMed

Identifiers

PMID: 9973492

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9973492-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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