Article
Manganese superoxide dismutase (MnSOD) genetic polymorphisms, dietary antioxidants, and risk of breast cancer.
Cancer research - 1 Feb 1999
Ambrosone C B, Freudenheim J L, Thompson P A, Bowman E, Vena J E, Marshall J R, Graham S, Laughlin R, Nemoto T, Shields P G
Abstract excerpt
Oxidative stress, resulting from the imbalance between prooxidant and antioxidant states, damages DNA, proteins, cell membranes, and mitochondria and seems to play a role in human breast carcinogenesis. Dietary sources of antioxidants (chemical) and endogenous antioxidants (enzymatic), including...
Topics
- Aged
- Alleles
- Antioxidants
- Breast Neoplasms
- Diet
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Risk Factors
- Superoxide Dismutase
