Article
Manganese superoxide dismutase Ala-9Val polymorphism, environmental modifiers, and risk of breast cancer in a German population.
Cancer causes & control : CCC - 1 Oct 2006
Slanger Tracy E, Chang-Claude Jenny, Wang-Gohrke Shan
Abstract excerpt
OBJECTIVE: A functional polymorphism at codon 16 (Alanine-to-Valine) of manganese superoxide dismutase (MnSOD) has been hypothesized to increase the risk of breast cancer and to modify the effects of oxidative stress. However, study findings have been inconsistent and sample sizes often small. METHODS: We used a large population-based age-matched case-control study in German Caucasian women up to age 50 to assess...
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