Article
Relationship between polymorphism in the manganese superoxide dismutase gene and breast cancer.
Mutation research - 1 Jan 2000
Eras-Erdogan N, Akbas E, Senli H, Kul S, Colak T
Abstract excerpt
Manganese superoxide dismutase (MnSOD) acts as an antioxidant and protects cells from the harmful effects of reactive oxygen species. We investigated the relationship between the MnSOD Ala-9Val polymorphism and breast cancer. Genotypes of 250 cases and 330 controls were determined by use of PCR-RFLP. Compared with the MnSOD Val/Val genotype, the MnSOD Val/Ala or MnSOD Ala/Ala genotype was not significantly...
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