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Article

Relationship between polymorphism in the manganese superoxide dismutase gene and breast cancer.

Mutation research - 1 Jan 2000

Eras-Erdogan N, Akbas E, Senli H, Kul S, Colak T

Abstract excerpt

Manganese superoxide dismutase (MnSOD) acts as an antioxidant and protects cells from the harmful effects of reactive oxygen species. We investigated the relationship between the MnSOD Ala-9Val polymorphism and breast cancer. Genotypes of 250 cases and 330 controls were determined by use of PCR-RFLP. Compared with the MnSOD Val/Val genotype, the MnSOD Val/Ala or MnSOD Ala/Ala genotype was not significantly...

Topics

Breast Neoplasms
Case-Control Studies
Female
Gene Frequency
Genetic Predisposition to Disease
Humans
Middle Aged
Polymorphism, Single Nucleotide
Risk Factors
Superoxide Dismutase
Turkey

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Identifiers

PMID: 19712751
DOI: 10.1016/j.mrgentox.2009.08.006

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