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Article

Target sequence polymorphism of human manganese superoxide dismutase gene and its association with cancer risk: a review.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2008

Bag Arundhati, Bag Niladri

Abstract excerpt

In normal state of a cell, endogenous antioxidant enzyme system maintains the level of reactive oxygen species generated by mitochondrial respiratory chain. Mitochondrial superoxide dismutase [SOD; manganese SOD (MnSOD) or SOD2] neutralizes highly reactive superoxide radical (O(*-)(2)), the first member in the plethora of mitochondrial reactive oxygen species. A polymorphism in the target sequence of MnSOD...

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Identifiers

PMID: 19064542
DOI: 10.1158/1055-9965.EPI-08-0235

Genes

SOD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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