Article
Role of the pre-S2 domain of the large envelope protein in hepatitis B virus assembly and infectivity.
Journal of virology - 1 Jul 1998
Le Seyec J, Chouteau P, Cannie I, Guguen-Guillouzo C, Gripon P
Abstract excerpt
Among the three viral proteins present in the hepatitis B virus (HBV) envelope, both the small and large polypeptides, but not the middle polypeptide, are necessary for the production of complete viral particles. Whereas it has been established that the C-terminal extremity of the pre-S1 region is required for HBV morphogenesis, whether the pre-S2 region of the large surface protein plays a critical role remains...
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