Role of the pre-S2 domain of the large envelope protein in hepatitis B virus assembly and infectivity.

doi:10.1128/JVI.72.7.5573-5578.1998

Back to search

Article

Role of the pre-S2 domain of the large envelope protein in hepatitis B virus assembly and infectivity.

Journal of virology - 1 Jul 1998

Le Seyec J, Chouteau P, Cannie I, Guguen-Guillouzo C, Gripon P

Abstract excerpt

Among the three viral proteins present in the hepatitis B virus (HBV) envelope, both the small and large polypeptides, but not the middle polypeptide, are necessary for the production of complete viral particles. Whereas it has been established that the C-terminal extremity of the pre-S1 region i...

Topics

Adult
Hepatitis B Surface Antigens
Hepatitis B virus
Humans
Mutation
Nucleocapsid
Protein Precursors
Tumor Cells, Cultured
Virion
Virus Assembly

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.