New p53-based anti-cancer therapeutic strategies.

doi:10.1007/BF02787204

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Article

New p53-based anti-cancer therapeutic strategies.

Medical oncology (Northwood, London, England) - 1 Dec 1998

Wiman K G

Abstract excerpt

The p53 gene is frequently mutated in human tumours and therefore an important target for therapeutic intervention. Several p53-based strategies for treatment of cancer are currently under development. p53 gene therapy has resulted in tumour regression in patients with lung cancer. A mutant adeno...

Topics

Adenoviridae
Clinical Trials as Topic
Gene Expression Regulation, Neoplastic
Genes, p53
Genetic Therapy
Genetic Vectors
Humans
Mutation
Neoplasms
Retroviridae
Tumor Suppressor Protein p53

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