Article
Effect of serum starvation on expression and phosphorylation of PKC-? and p53 in V79 cells: Implications for cell death
29 Jan 1999
Abstract excerpt
The effect of serum starvation on the expression and phosphorylation of PKC-alpha and p53 in Chinese hamster V79 cells was investigated. Serum starvation led to growth arrest, rounding up of cells and the appearance of new PKC-alpha and p53 bands on Western blots. Prolonged incubation (> or = 48 hr) in serum-deprived medium led to cell detachment and death. Moving cells to fresh medium containing 10% serum...
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