Article
Wild-type p53 gene-induced morphological changes and growth suppression in hepatoma cells.
Journal of gastroenterology - 1 Jun 1997
Terai S, Noma T, Kimura T, Nakazawa A, Kurokawa F, Okita K
Abstract excerpt
The human hepatocellular carcinoma (HCC) cell line, HLF, expresses only mutant-type p53 (mt-p53), which has an amino acid substitution at the 244th residue from glycine to alanine. HLF cells were transfected with wild-type p53 (wt-p53) cDNA construct pC53-SN3, mt-p53 cDNA construct pC53-SCX [whic...
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