Article
Selective degradation of the PKC-epsilon isoform during cell death in AKR-2B fibroblasts.
Experimental cell research - 15 May 2001
Hoppe J, Hoppe V, Schäfer R
Abstract excerpt
The protein kinase C (PKC) family of serine/threonine protein kinases is involved in intracellular signals that regulate growth, differentiation, and apoptosis. AKR-2B cells express the PKC isoforms alpha, gamma, epsilon, lambda, mu, und zeta (J. Hoppe, R. Schäfer, V. Hoppe, and A. Sachinidis, Cell Death Differ. 6, 546-556). Here we show that during serum starvation only PKC-epsilon was cleaved. An N-terminal...
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