Polymerase chain reaction-single strand conformation polymorphism or how to detect reliably and efficiently each sequence variation in many samples and many genes.

doi:10.1002/elps.1150191802

Back to search

Article

Polymerase chain reaction-single strand conformation polymorphism or how to detect reliably and efficiently each sequence variation in many samples and many genes.

Electrophoresis - 1 Dec 1998

Jaeckel S, Epplen J T, Kauth M, Miterski B, Tschentscher F, Epplen C

Abstract excerpt

A simple and fast method with high reliability is necessary for the identification of mutations, polymorphisms and sequence variants (MPSV) within many genes and many samples, e.g. to clarify the genetic background of individuals with multifactorial diseases. We evaluated polymerase chain reactio...

Topics

Genetic Predisposition to Disease
Genetic Variation
Humans
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Reproducibility of Results

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.