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Article

PCR-SSCP: a method for the molecular analysis of genetic diseases.

Molecular biotechnology - 1 Feb 2008

Kakavas V Konstantinos, Konstantinos Kakavas V, Plageras Panagiotis, Panagiotis Plageras, Vlachos T Antonios, Antonios Vlachos T, Papaioannou Agelos, Agelos Papaioannou, Noulas V Argiris, Argiris Noulas V

Abstract excerpt

Single strand conformation polymorphism (SSCP) is a reproducible, rapid and quite simple method for the detection of deletions/insertions/rearrangements in polymerase chain reaction amplified DNA. All the details for the use of PCR-SSCP are presented in the direction of genetic diseases (beta-thalassaemia, cystic fibrosis), optimum gel conditions, sensitivity and the latest modifications of the method, which are...

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Source

Identifiers

PMID: 18219595
DOI: 10.1007/s12033-007-9006-7

Genes

CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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