Article
The gene encoding atrial natriuretic peptide and the risk of human stroke.
Circulation - 19 Oct 1999
Rubattu S, Ridker P, Stampfer M J, Volpe M, Hennekens C H, Lindpaintner K
Abstract excerpt
BACKGROUND: Recent evidence from an animal model of stroke, the stroke-prone spontaneously hypertensive rat, implicated the gene encoding atrial natriuretic peptide (ANP) as a possible candidate contributing to the likelihood of experiencing a stroke. The purpose of the present study was to investigate the role of ANP in the pathogenesis of cerebrovascular accidents in humans. METHODS AND RESULTS: We investigated...
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