Article
?2-Adrenergic Receptor Subtypes ? Novel Functions Uncovered in Gene-Targeted Mouse Models
21 Apr 2004
Abstract excerpt
The family of adrenergic receptors contains nine different subtypes of G protein-coupled receptors which mediate the biological effects of adrenaline and noradrenaline. With few exceptions, the full therapeutic potential of subtype-selective therapy has not yet been explored for the group of adrenergic receptors. In the absence of sufficiently subtype-selective ligands which can distinguish between individual...
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