Paramyxovirus fusion protein: characterization of the core trimer, a rod-shaped complex with helices in anti-parallel orientation.

doi:10.1006/viro.1998.9532

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Article

Paramyxovirus fusion protein: characterization of the core trimer, a rod-shaped complex with helices in anti-parallel orientation.

Virology - 1 Feb 1999

Dutch R E, Leser G P, Lamb R A

Abstract excerpt

The fusion (F) protein of the paramyxovirus SV5 contains two heptad repeat regions, HRA adjacent to the fusion peptide and HRB proximal to the transmembrane domain. Peptides, N-1 and C-1, respectively, corresponding to these heptad repeat regions form a thermostable, alpha-helical trimer of heter...

Topics

Amino Acid Sequence
Animals
Chymotrypsin
Leucine Zippers
Microscopy, Electron
Molecular Sequence Data
Mutation
Papain
Peptides
Respirovirus
Temperature
Viral Fusion Proteins

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