Article
A conserved region in the F(2) subunit of paramyxovirus fusion proteins is involved in fusion regulation.
Journal of virology - 1 Aug 2007
Gardner Amanda E, Dutch Rebecca E
Abstract excerpt
Paramyxoviruses utilize both an attachment protein and a fusion (F) protein to drive virus-cell and cell-cell fusion. F exists functionally as a trimer of two disulfide-linked subunits: F(1) and F(2). Alignment and analysis of a set of paramyxovirus F protein sequences identified three conserved blocks (CB): one in the fusion peptide/heptad repeat A domain, known to play important roles in fusion promotion, one...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
