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Article

Genetic and environmental risk factors for submucous cleft palate.

European journal of oral sciences - 1 Apr 2012

Reiter Rudolf, Brosch Sibylle, Lüdeke Manuel, Fischbein Elena, Haase Stephan, Pickhard Anja, Assum Günter, Schwandt Anke, Vogel Walther, Högel Josef, Maier Christiane

Abstract excerpt

A multifactorial aetiology with genetic and environmental factors is assumed for orofacial clefts. Submucous cleft palate (SMCP), a subgroup of cleft palates with insufficient median fusion of the muscles of the soft palate hidden under the mucosa, has a prevalence of 1:1,250-1:5,000. We described the prevalence of risk factors among 103 German patients with the subtype SMCP and genotyped 24 single nucleotide...

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Source

Identifiers

PMID: 22409215
DOI: 10.1111/j.1600-0722.2012.00948.x

Genes

SMCP
TGFB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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