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Article

Review article: the genetics of inflammatory bowel disease.

Alimentary pharmacology & therapeutics - 1 Jun 2001

Ahmad T, Satsangi J, McGovern D, Bunce M, Jewell D P

Abstract excerpt

Recent epidemiological, clinical and molecular studies have provided strong evidence that inherited predisposition is important in the pathogenesis of chronic inflammatory bowel diseases. The model most consistent with the epidemiological data suggests that Crohn's disease and ulcerative colitis are related polygenic diseases, sharing some but not all susceptibility genes. Investigators throughout the world have...

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PMID: 11380312
DOI: 10.1046/j.1365-2036.2001.00981.x

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