Article
Genetics of inflammatory bowel disease. A personal view on progress and prospects.
Digestive diseases (Basel, Switzerland) - 1 Jan 2000
Satsangi J, Jewell D, Parkes M, Bell J
Abstract excerpt
Clinical, epidemiological and molecular data reported in the last 5 years have provided strong evidence that genetic factors are important in susceptibility to both Crohn's disease and ulcerative colitis. The model of disease inheritance which best fits the epidemiological data is that Crohn's disease and ulcerative colitis are related polygenic diseases. However, genetic heterogeneity is likely to be extensive,...
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