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Article

Genetic aspects of inflammatory bowel disease: how far have we come, and where are we heading?

Current gastroenterology reports - 1 Dec 1999

Cho J

Abstract excerpt

Crohn"s disease and ulcerative colitis are related complex genetic disorders, with gene-gene and gene-environment interactions that are critical to their pathogenesis. Multiple genetic loci have been implicated through genome-wide searches. Of these, a locus on Crohn"s disease has been definitively established in the pericentromeric region of chromosome 16. Multiple candidate gene studies have been forwarded, and...

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PMID: 10980992
DOI: 10.1007/s11894-999-0009-3

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