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[CYP2D6 genotypes and phenotypes in Chinese Han, Uygur and Kazakh populations].

Yao xue xue bao = Acta pharmaceutica Sinica - 1 Feb 2011

Li Guo-chang, Yang Jun, Zhou Ting, Chen Zhi-gang, Chen Wen

Abstract excerpt

This study is to compare the influence of CYP2D6 *3 and *4 genotypes and phenotypes on the metabolic activity of CYP2D6 in Chinese Han, Uygur and Kazakh ethnic groups. Allele specific amplification (ASA) was used to determine the CYP2D6*3 and CYP2D6*4 genotypes. Phenotypes of CYP2D6 in all subjects were determined using dextromethorphan as probe drug by HPLC methods. Among the 132 Han subjects, one subject...

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PMID: 21542297

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