Article
CYP2D6 genetic polymorphism in South Indian populations.
Biological & pharmaceutical bulletin - 1 Aug 2006
Naveen Amrithraj Theophilus, Adithan Chandrasekaran, Soya Sisy Sam, Gerard Nathalie, Krishnamoorthy Rajagopal
Abstract excerpt
This study aimed to determine the prevalence of genetic polymorphism in the CYP2D6 gene, which codes for the polymorphically expressed CYP2D6 drug-metabolizing enzyme. The common variants CYP2D6 *2, *3, *4, *5, *10, *14, and *17 were studied in the populations (n=447) of the four South Indian states namely Tamilnadu (TN), Kerala (Ker), Karnataka (Kar) and Andhra Pradesh (AP). Genetic polymorphisms were identified...
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