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Article

p53 protein overexpression and gene mutation in mixed Müllerian tumors of the uterus.

Cancer detection and prevention - 1 Jan 1999

Soong R, Knowles S, Hammond I G, Michael C, Iacopetta B J

Abstract excerpt

Alteration of the p53 tumor suppressor gene is associated with poor prognosis in many human cancer types. We examined the incidence and prognostic significance of p53 gene alterations in a series of uterine malignant mixed Müllerian tumors (MMT). Nuclear overexpression of p53 protein detected by immunohistochemistry (IHC) with the DO-7 antibody was observed in 12 of 24 (50%) tumors. Mutation of the p53 gene...

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PMID: 9892985
DOI: 10.1046/j.1525-1500.1999.00062.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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