Article
p53 immunoreactivity and mutation of the p53 gene in smooth muscle tumours of the uterine corpus.
The Journal of pathology - 1 Sept 1995
Jeffers M D, Farquharson M A, Richmond J A, McNicol A M
Abstract excerpt
Mutation and overexpression of p53 have been described in uterine malignant mixed Müllerian tumours and in endometrial adenocarcinoma, where it has been associated with a poor prognosis. This study examines p53 expression and mutation of the p53 gene in benign and malignant smooth muscle tumours...
Topics
- Base Sequence
- Female
- Gene Expression
- Genes, p53
- Humans
- Immunoenzyme Techniques
- Leiomyosarcoma
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Survival Rate
- Tumor Suppressor Protein p53
- Uterine Neoplasms